What is photodynamic therapy, and what can it be used to treat?

If you have been diagnosed with actinic keratoses (AKs), superficial basal cell carcinomas (sBCCs) or sun damage, working with a dermatologist for treatment is the first step in caring for your skin concerns. At Clear Skin Dermatology, our experienced provider, Dr. Sanjay Siddha, may recommend using Metvix photodynamic therapy to treat multiple AKs, sBCCs and sun damage year-round. It provides the confidence of an in-office solution with no at-home applications, making it a highly desirable option for many of our patients.

What is photodynamic therapy?

Photodynamic therapy, sometimes referred to by its acronym PDT, is a specific type of treatment that uses special drugs, known as photosensitizing agents, along with light to kill cancer cells. It is often used for skin conditions like actinic keratoses and superficial basal cell carcinomas. The photosensitizing agent is applied to the affected area and is then activated by a specific type of light, destroying abnormal cells.

Sun Damaged Skin

Photo courtesy of Galderma

How do I prepare for my upcoming Metvix photodynamic therapy appointment?

Our team will educate you on how to get ready for your appointment. We advise patients to bring an extra shirt or hoodie with them to their appointment, as the spraying of cold water on the skin can cause clothing to be affected. Then, a prescription cream that has been stored to remain cold will be applied to the skin, and we will walk patients through the treatment process so there are no surprises!

What are the possible side effects of Metvix photodynamic therapy?

Some of the more common effects seen in our patients may include:

  • Flaking and peeling of the skin.
  • Swelling and redness.
  • Temporary dark spots/pigmentation areas.
  • Burning and stinging in the first 24 hours.
  • Small pimples or Millia.
  • Blisters.

Frequently Asked Questions About Photodynamic Therapy

Who is a good candidate for photodynamic therapy?

Photodynamic therapy may be recommended for patients with multiple actinic keratoses, certain superficial basal cell carcinomas, or areas of visible sun damage that need professional treatment. Good candidates are usually patients who want an in-office option and can follow aftercare instructions carefully, especially sun avoidance after treatment. Dr. Sanjay Siddha will examine your skin, review your diagnosis, and determine whether Metvix photodynamic therapy is appropriate for your specific condition, skin type, medical history, and treatment goals.

How long does a photodynamic therapy appointment usually take?

The length of your appointment can vary depending on the size of the treatment area and the protocol being used. In many cases, patients should plan for more than just a quick office visit because the photosensitizing medication may need time to be absorbed into the skin before light activation begins. Clear Skin Dermatology will explain the expected timing before your appointment so you can plan your day comfortably, arrange transportation if needed, and avoid feeling rushed during treatment.

What should I expect my skin to look like after treatment?

After photodynamic therapy, the treated area may look red, irritated, swollen, or sunburned for a period of time. Some patients notice peeling, crusting, or temporary darkening as damaged cells respond to treatment and the skin begins to renew itself. The intensity of the reaction can vary from person to person. Dr. Siddha’s team will explain what changes are expected, how long they may last, and which symptoms should prompt a call to the office.

How long should I avoid sunlight after photodynamic therapy?

Sun protection is extremely important after photodynamic therapy because the treated skin can remain more sensitive to light for a short period. You may be instructed to avoid direct sunlight, bright outdoor exposure, and certain intense indoor lights for the recommended period after treatment. Protective clothing, wide-brimmed hats, and staying indoors as directed can help reduce the risk of unnecessary irritation. Clear Skin Dermatology will provide specific aftercare instructions based on your treatment.

Can photodynamic therapy be repeated if I have ongoing sun damage?

Yes. Some patients benefit from more than one photodynamic therapy session, especially if they have widespread sun damage or recurring precancerous lesions. The number and frequency of treatments depend on your diagnosis, response to therapy, and overall skin cancer risk. Dr. Siddha may also recommend periodic skin checks to monitor treated areas and identify new concerns early. Ongoing dermatologic care is especially important for patients with a history of actinic keratoses or skin cancer.

Is photodynamic therapy used instead of regular skin cancer checks?

No. Photodynamic therapy can treat specific diagnosed skin concerns, but it does not replace routine dermatology examinations. Patients with actinic keratoses, superficial basal cell carcinomas, or significant sun damage still need professional skin monitoring because new lesions can develop over time. Regular skin checks allow Dr. Siddha to evaluate suspicious spots, track changes, and recommend timely treatment when needed. PDT is one part of a broader plan for protecting long-term skin health.

How should I care for my skin while it heals?

After treatment, gentle skin care is best. Use only products recommended by Clear Skin Dermatology, avoid picking or scrubbing peeling areas, and protect the treated skin from sun exposure as instructed. Moisturizer may be recommended to ease dryness or tightness, and cool compresses may help with temporary discomfort. Avoid harsh exfoliants, retinoids, or irritating products until you are told it is safe to restart them. Following aftercare directions helps support smoother, more comfortable healing and may reduce the chance of prolonged redness, irritation, or unnecessary delays in returning to your normal skin care routine. 

Schedule an appointment with Clear Skin Dermatology today!

If you reside in or around the areas of Toronto or Newmarket, Ontario and want to speak to Dr. Sanjay Siddha and his team about the benefits of Metvix photodynamic therapy, we invite you to call our office to request a consultation visit to learn more about this and other services readily available at our state-of-the-art practice. We are open to new and returning patients and welcome you into our office for quality, comprehensive skin care by an experienced dermatologist. Please call our Toronto office at (416) 963-5955 or our New Market office at (905) 235-5232.